Diagnostic Values of Some Immunological Markers in Patients With Urinary Tract Infection

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Thekra Ahmed Hamada AL-Tikrity
Marwa Tariq Ahmed Al-Douri
Nihad Nejres Hilal
Mohammed Mohsin Abdul- Aziz

Abstract

The study was carried out in Tikrit city from January 1st to July 1st 2015. These patients admitted to Sallah Al-Deen general hospital and primary health care centers in Tikrit city. The number of patients with Urinary tract infection was 300 patients whom their ages ranged from 2 months to 70 years. The control group included 100 individuals who appeared healthy with no history of UTI. A urine direct and indirect examination was held for all the patients and control. The result showed 70 % positive specimens in culture media. Most isolates were Staph. aureus with 25%. Staph. saprophyticus 24% , E. coli 16%, K. pneumoneae 5% . Pseudomonas aeruginosa, and Proteus Spp. and Citrobacter frundii were present in about 5% and 7%, respectively. A member of (yeast-like fungi) Candida Spp. was also found in the ear in about 11%. Blood analysis showed that there was a significant increase in WBC, ESR, neutrophil, and CRP in UTI patients compared to the control group. Serum cytokines showed that the mean level of serum IL-1 family (IL-1α and IL-1β), IL-6, and IL-8 in addition to TNF-α, all were significantly higher in UTI patients than in the control group. Also, results showed a significant increase in serum cytokines in UTI patients with gram-negative bacteria in comparison with gram-negative bacteria.
Conclusion: A significant difference was found between patients with UTI and control group regarding some immunological markers. They are also can differentiate between gram-positive and negative UTI.


How to cite this article: Miranda, F.C., Kamath, K.K. and Shabaraya, A.R. (2019). Diagnostic Values of Some Immunological Markers in Patients With Urinary Tract Infection. International Journal of Drug Delivery Technology, 9(4): 635-639.


Source of support: Nil.
Conflict of interest: None.

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Research Article